Cardiac Dysfunction

Treatment With Crocin Improves Cardiac Dysfunction by Normalizing Autophagy and Inhibiting Apoptosis in STZ-induced Diabetic Cardiomyopathy Abstract Background and aim: The association of diabetes mellitus (DM) and poor metabolic control…

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Recognition Memory

Effects of the Active Constituents of Crocus Sativus L. Crocins and Their Combination With Memantine on Recognition Memory in Rats Abstract Crocus sativus L., is a plant cultivated in many…

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Sexual Behaviors

The Effect of Saffron, Crocus Sativus Stigma, Extract and Its Constituents, Safranal and Crocin on Sexual Behaviors in Normal Male Rats Abstract In this study, the aphrodisiac activities of Crocus…

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Hemostasis and Atherosclerosis

The Effect of Saffron (Crocus sativus) Carotenoids on Hemostasis and Atherosclerosis Abstract In current review is described in short the findings indicating that Crocus sativus exerts antithrombotic and antiatherosclerosis effect.…

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Phytochemical Differentiation

Quantitation of Crocins and Picrocrocin in Saffron by HPLC: Application to Quality Control and Phytochemical Differentiation From Other Crocus Taxa Abstract A chromatographic method was developed and fully validated for…

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Hydrocarbon Loss

In-chain Neutral Hydrocarbon Loss From Crocin Apocarotenoid Ester Glycosides and the Crocetin Aglycon (Crocus Sativus L.) by ESI-MS(n) (n=2, 3) Abstract The stigmas of Crocus sativus L. have been used…

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Behavioural Deficits

Crocins, the active constituents of Crocus Sativus L., counteracted ketamine-induced behavioural deficits in rats Abstract Experimental evidence indicates that the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine impairs cognition and can…

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Source of Novel Acetylcholinesterase Inhibitors

Saffron as a Source of Novel Acetylcholinesterase Inhibitors: Molecular Docking and in Vitro Enzymatic Studies Abstract Inhibitors of acetylcholine breakdown by acetylcholinesterase (AChE) constitute the main therapeutic modality for Alzheimer's…

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Analysis of Crocins and Picrocrocin

Comparison of Different Tandem Mass Spectrometric Techniques (ESI-IT, ESI- And IP-MALDI-QRTOF and vMALDI-TOF/RTOF) for the Analysis of Crocins and Picrocrocin From the Stigmas of Crocus Sativus L Abstract Rationale: The…

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